What is the appropriate administration method and dosage for sodium bicarbonate in salicylate poisoning?

The appropriate administration method for sodium bicarbonate in cases of salicylate poisoning is intravenous, specifically through the administration of 50 mL of 8.4% solution. This technique is endorsed in situations where there is severe metabolic acidosis, which can occur during salicylate toxicity.

Sodium bicarbonate functions by serving as a bicarbonate buffer, helping to raise the serum pH and improve the elimination of salicylate from the body. When given intravenously, it allows for rapid and controlled delivery, ensuring that the medication is effectively introduced into the bloodstream to counteract the acid-base imbalance that salicylate poisoning can cause.

Other administration routes and dosages, such as intramuscularly, orally, or subcutaneously, are not suitable for addressing salicylate poisoning. Intramuscular delivery would provide a delayed response, which is not ideal in acute poisoning situations. Oral administration is inconsistent for immediate treatment and cannot swiftly manage life-threatening complications. Subcutaneous administration also presents the same issues as intramuscular and is less effective in urgent interventions, particularly when intravenous access can provide a more direct and immediate way to mitigate the effects of the poisoning. Thus, the intravenous route with the specified dosage aligns with the