What is the first step in the management of sepsis?

The first step in the management of sepsis is to start antibiotics immediately. Early initiation of broad-spectrum intravenous antibiotics is crucial because sepsis is a time-sensitive condition that can rapidly lead to organ dysfunction and increased mortality. The prompt administration of antibiotics targets the underlying infection, which is essential for improving patient outcomes.

While taking blood cultures is important for identifying the causative organism and tailoring antibiotic therapy, it should not delay the administration of antibiotics. Therefore, although blood cultures are a critical step in sepsis management, they follow the immediate treatment with antibiotics to ensure that effective therapy starts as soon as possible.

Monitoring urine output and administering IV fluids are also important components of sepsis management, but they are generally considered secondary to the need for immediate antibiotic therapy. Timely intervention with antibiotics is vital in the early phase of treatment, which directly addresses the septic process.