What is the recommended dosage of Ipratropium bromide for severe asthma management?

The recommended dosage of Ipratropium bromide for the management of severe asthma is 500 mcg administered every 4-6 hours. This particular dosage is aimed at achieving effective bronchodilation, which is critical in acute asthma exacerbations. Ipratropium bromide is an anticholinergic medication that works by inhibiting bronchoconstriction, thus helping to improve airflow and alleviate acute respiratory distress.

In the context of treating severe asthma, a higher dosage of 500 mcg is typically indicated compared to standard or less severe cases. This dosage is balanced with safety considerations for frequent administration while ensuring optimal therapeutic effect, allowing for better management of airway obstruction.

Lower dosages, such as those in other options, may not provide the necessary bronchodilatory effect required in the acute phase of severe asthma. The recommended interval of 4-6 hours is also designed to allow for multiple doses while reducing the risk of potential side effects associated with more frequent dosing.