When should adrenaline be administered in ALS?

Adrenaline should be administered every 3-5 minutes, specifically after every other shock during cardiac arrest management. This timing is crucial because adrenaline (also known as epinephrine) plays a key role in increasing coronary and cerebral perfusion pressure, which enhances the chances of return of spontaneous circulation (ROSC) when given in conjunction with defibrillation.

Administering it every 3-5 minutes allows for proper intervals based on the rhythm check and defibrillation cycles, optimizing its effectiveness without the risk of overdosing, which can occur if given too frequently. It aligns with the structured approach in ALS guidelines, which emphasize the coordination of rhythm assessment and the timing of medication administration.

Using adrenaline at every shock or on too frequent a schedule could lead to unnecessary complications and might not provide the benefits intended. Hence, the strategy of administering it every 3-5 minutes after every other shock is essential for maximizing the potential positive outcomes during advanced life support interventions.